ТHROMBIN ACTIVITY AND EARLY OUTCOME IN UNSTABLE ANGINA PECTORIS

Authors

  • Кhakimova M.A Tashkent Medical Academy, Uzbekistan. Author

Keywords:

Methods and Results Plasma concentrations and 24-hour urinary excretion of fibrinopeptide A were prospectively determined in 150 patients with unstable angina.

Abstract

Background. The blood coagulation system is frequently activated in the acute phase of unstable angina, but it is unknown whether the augmented function of the hemostatic mechanism may serve as a marker of increased risk for an early unfavorable outcome.

References

1. Болезни сердца по Браунвальду: руководство по сердечно-сосудистой медицине. Под ред. П. Либби; пер. с англ. под общ. ред.Р.Г. Оганова: в 4 т. Т. 1. Главы 1–20. М.: Рид Элсивер 2020; 101–120.

2. Онучина Е.Л., Соловьев О.В., Мочалова О.В. Пациент с метаболическим синдромом: факторы риска развития фибрилляции предсердий. Практическая медицина 2021; 4 (43): 139–142.

3. Рекомендации по количественной оценке структуры и функции камер сердца. Российский кардиологический журнал 2022; 3 (95): 3–28.

4. Эрлих Д.А. Острый коронарный синдром и сопутствующая патология: характеристики пациентов, особенности лечения и исходы за время госпитализации. Ишемическая болезнь сердца 2024; Consilium medicum 2024; 16 (5): 33–37.

5. Abed H.S., Wittert G.A., Leong D.P. Effect of weight reduction and cardiometabolic risk factor management on symptom burden and severity in patients with atrial fibrillation: a randomized clinical trial. JAMA 2023; 310 (19): 2050–2060.

6. Alonso A., Lopez F.L., Matsushita K. Chronic kidney disease is associated with the incidence of atrial fibrillation: the Atherosclerosis Risk in Communities (ARIC) study. Circulation 2022; 123 (25): 2946–2953.

7. Anter E., Jessup M., Callans D.J. Atrial, fibrillation and heart failure: treatment considerations for a dual epidemic. Circulation 2009; 119: 2516–2525.

8. Bansal N. Intersection of cardiovascular disease and kidney disease: atrial fibrillation. Curr Opin Nephrol Hypertens 2024; 23 (3): 275–282.

9. Devereux R.B., Alomso D.R., Lutas E.M. Echocardiographic assessment of left ventricular hypertrophy comparison to necropsy findings. Am J Cardiol 2019; 57: 450–458.

10. Go A.S., Hylek E.M., Phillips K.A. Prevalence of diagnosed atrial fibrillation in adults: national implications for rhythm management and stroke prevention: the anticoagulation and risk factors in atrial fibrillation (ATRIA) study. J Amer Med Assoc 2021; 285: 2370–2375.

11. Jabre P., Roger V.L., Murad M.H. Mortality associated with atrial fibrillation in patients with myocardial infarction: a systematic review and meta-analysis. Circulation 2021; 123 (15): 1587–1593.

12. Kinjo K. Prognostic significance of atrial fibrillation. Am J Cardiol 2023; 92: 1150–1154.

13. Lehto M. Prognostic risk of atrial fibrillation in acute myocardial infarction complicated by left ventricular dysfunction: the OPTIMAAL experience. Eur Heart J 2025; 26: 350–356.

14. Roberts P.R. Arrhythmias in chronic kidney disease. Heart 2021; 97 (9): 766–773.

15. Roy D., Talajic M., Thibault B. Pilot study and protocol of the Canadian Trial of

Atrial Fibrillation (CTAF). Am J Cardiol 2020; 80 (4): 464–468.

16. Saczynski J.S., McManus D., Zhou Z. Trends in atrial fibrillation complicating acute

myocardial infarction. Am J Cardiol 2009; 104 (2): 169–174.

17. Schmitt J., Duray G., Gersh B.J. Atrial fibrillation in acute myocardial infarction: a systematic review of the incidence, clinical features and prognostic implications. European Heart Journal 2009; 30 (9): 1038–1045.

18. Torres M., Rocha S., Marques J. Impact of atrial fibrillation in acute coronary syndromes. Rev Port Cardiol 2020; 27 (11):1407–1418.

19. Whitlock G. Body- mass index and cause specific mortality in 900,000 adults: collaborative analyses of 57 prospective studies. Lancet 2021; 373: 1083–1096.

20. Zimmerman D., Sood M.M., Rigatto C. Systematic review and meta-analysis of incidence, prevalence and outcomes of atrial fibrillation in patients on dialysis. Nephrol Dial Transplant 2022; 27: 3816–3822

Downloads

Published

2025-10-18