YURAK TO’QIMALARINING GIPOKSIYA HOLATIDAGI GISTOLOGIK O’ZGARISHLAR.
Keywords:
Hujayra o’zaro ta’siri, metabolizm, gipoksiya, ishemik gipoksiya, gipoksemik gipoksiya, gistotoksik gipoksiya, miokard ,hujayra shishi ,mitoxondriyalarning shishi.Abstract
Gipoksiya – bu organizmda kislarod yetishmovchiligi bo’lib, butun organizmga hamda yurak to’qimalariga salbiy ta’sir ko’rsatadi. Shuningdek, miokard yuqori metabolik faollikka ega bo’lib, maqolada gipoksik sharoitda yurak to’qimalarida kuzatiladigan gistologik o’zgarishlar, ya’ni morfologik o’zgarishlar, hujayraviy moslashuvlar va patalogik natijalarni ko’rib chiqamiz. Bu o’zgarishlarni tushunish, yurak ishemik kasalliklarini aniqlash va davolashda muhim ahamiyatga ega.
References
1. Rakhimov R. A. Patologik anatomiya. — Toshkent: Tibbiyot, 2018.
2. Robbins S. L., Cotran R. S. Pathologic Basis of Disease. 10th ed. — Elsevier, 2020.
3. Kumar V., Abbas A., Aster J. Robbins & Cotran Pathologic Basis of Disease. 9th ed. — Elsevier Saunders, 2015.
4. Semenza G. L. Hypoxia-inducible factors in physiology and medicine. Cell, 2012.
5. Heusch G. Molecular basis of cardioprotection. Circulation Research, 2015.
6. Eltzschig H. K., Carmeliet P. Hypoxia and inflammation. NEJM, 2011.
7. Turer A. T., Hill J. A. Pathogenesis of myocardial ischemia-reperfusion injury. Am J Cardiol, 2010.
8. WHO. Cardiovascular Diseases (CVDs) Fact Sheet, 2023.
9. Carmeliet P. Angiogenesis in life and disease. Nature, 2005.
10. Chandel N. S. Navigating Metabolism. Cold Spring Harbor Laboratory Press, 2015
11. https://www.sciencedirect.com/science/article/pii/S2452302X24004583
