SEROTYPE DIVERSITY OF S. PNEUMONIAE IN NASOPHARYNGEAL CARRIAGE AMONG HEALTHY CHILDREN AFTER VACCINATION: ASSESSMENT OF VACCINE PREVENTION EFFECTIVENESS
Keywords:
To evaluate the effectiveness of pneumococcal vaccination by studying the serotype diversity of S. pneumoniae in nasopharyngeal carriage among healthy vaccinated children.Abstract
Nasopharyngeal carriage of Streptococcus pneumoniae is considered one of the main factors contributing to the transmission and spread of pneumococcal infections among children. Continuous monitoring of circulating pneumococcal serotypes is essential for evaluating epidemiological changes and determining the effectiveness of pneumococcal vaccination programs. Changes in the serotype landscape of invasive pneumococcal strains may lead to an increase in diseases caused by non-vaccine serotypes. This creates a need for further scientific research aimed at expanding the number of serotypes included in conjugate vaccines and improving preventive strategies against pneumococcal diseases.