PSORALEA CORYLIFOLIA L. O'SIMLIGIDAN AJRATILGAN PSORALENNING SITOTOKSIK FAOLLIGI.
Keywords:
hujayra biologiyasi usullari, sitotoksiklikni baholash usullari, fotodinamik terapiya.Abstract
21-asr texnologiyasi bo'lgan PDTning salohiyati tugamaydi. O'simliklardan olingan fotosensibilizatorlarning sitotoksik ta'sirining mexanizmlari asosan o'rganilmagan. Furanokumarinlarning fotodinamik xususiyatlari ultrabinafsha nurlanishni yutish orqali ularning molekulalari qo'zg'aluvchan holatga o'tishi va bu holatda qo'sh aloqalarni o'z ichiga olgan biologik muhim hujayra komponentlari bilan reaksiyaga kirishishi bilan izohlanadi. DNK tuzilishi va funktsiyasining buzilishi sitotoksiklik uchun juda muhimdir.
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