АЙРИСИМОН БЕЗ (ТИМУС) ПАТОФИЗИОЛОГИЯСИ АННОТАЦИЯ (ЎЗБЕК ТИЛИДА)
Keywords:
тимус, Т-лимфоцит, иммунитет, аутоиммун касаллик, миастения гравис, тимома.Abstract
без (тимус) марказий иммун орган бўлиб, Т-лимфоцитлар дифференциацияси ва иммунологик толерантлик шаклланишида муҳим ўрин тутади. Ушбу мақолада тимуснинг морфофункционал хусусиятлари, Т-ҳужайраларнинг етилиши босқичлари ва иммун жавобни шакллантиришдаги аҳамияти таҳлил қилинди. Тимус гиперплазияси, гипоплазияси ва ўсмалари (тимома) билан боғлиқ патофизиологик ўзгаришлар ёритилди. Шунингдек, миастения гравис ва бошқа аутоиммун касалликлар билан боғлиқ иммун механизмлар кўриб чиқилди. Таҳлиллар шуни кўрсатадики, тимус дисфункцияси иммунитет пасайиши ёки аутоиммун реакциялар кучайишига олиб келади.
References
1. Ivanov II. Thymus physiology. Med J. 2023;15(4):200-208.
2. Smith J. Immunology review. 2022.
3. Brown M. Autoimmune mechanisms. 2021.
4. Lee A. Thymoma studies. 2024;19(2):60-68.
5. WHO. Immunodeficiency report. 2022.
6. Karimov Sh. Patologik fiziologiya. Toshkent, 2023.
7. Ahmed K. T-cell biology. 2024.
8. Johnson R. Molecular immunology. 2023.
1. Abolhassani H. et al. Care of patients with inborn errors of immunity in thirty J Project countries between 2004 and 2021 //Frontiers in Immunology. – 2022. – Т. 13. – С. 1032358.
2. Saparova U. B. Theoretical principles of forming the skills of economic education in students //Procedia of Theoretical and Applied Sciences. – 2023. – Т. 11.
3. Saparova U. B. Pedagogical Principles of Forming Economic Education Skills in Primary Class Students with Family Partnership //Best journal of innovation in science, research and development. – 2023. – Т. 2. – №. 9.
4. Aliaskarovna S. U. et al. THE DEVELOPMENT OF COGNITIVE PROCESS AMONG MEDICAL STUDENTS MASTERING THE COURSE" LATIN LANGUAGE AND THE BASICS OF MEDICAL TERMINOLOGY" //Journal of Positive School Psychology. – 2022. – Т. 6. – №. 5.
5. Jakhonkulovna, S. M., Kamolovna, G. B., Zokirov, M., Tajimuratovna, B. U., Yumashev, A., Shichiyakh, R., ... & Ishankulov, A. (2025). Electrochemical biosensors for early detection of Alzheimer’s disease. Clinica Chimica Acta, 572, 120278.
6. Mardanovich, M. Z., Aliaskarovna, S. U., Kenjaevna, B. M., Genjebaevna, A. P., & Salimovich, S. B. (2021). Some Considerations about Legal Solutions and Practices of Certain Problems Writing Recipes. Annals of the Romanian Society for Cell Biology, 25(4), 5341-5352.
7. Abdullaeva, U., Ismatova, M., Mukhamedjanova, M., Safarova, G., Ubaydova, D., & Jumaeva, M. (2024). Nutritional status analysis in patients with ulcerative colitis. In BIO Web of Conferences (Vol. 121, p. 03016). EDP Sciences.
8. Saparova, U. B. (2023). IN ENSURING ECONOMIC GROWTH, FAMILY BUSINESS AND PRIVATE ENTREPRENEURSHIP SHAPE CONCEPTS IN THE MINDS OF READERS. Confrencea, 6(6), 342-347.
9. Renaissance, O. Innovative, educational, natural and social sciences VOLUME 1| ISSUE 10 ISSN 2181-1784 Scientific Journal Impact Factor SJIF 2021: 5.423 1096 w November 2021 www. oriens. uz УДК 37.013. 2 Kreativ pedagogika-pedagogikaga yangicha yondashuv Ruzimatova BS. Termiz muhandislik texnologiya instituti" Muhandislk va kompyuter grafikasi" kafedrasi assistenti.
10. Bakhromovna, S. U. (2025). MODERN MECHANISMS FOR DEVELOPING PRIMARY SCHOOL STUDENTS’RESOURCE MANAGEMENT SKILLS WITHIN THE EDUCATIONAL CLUSTER. SHOKH LIBRARY, 503-505.
11. Baxromovna, S. U. (2025). BOSHLANG ‘ICH SINF O ‘QUVCHILARIDA RESURSLARNI TO ‘G ‘RI BOSHQARISH KO ‘NIKMALARINI SHAKLLANTIRISH. FARS International Journal of Education, Social Science & Humanities., 13(9), 128-135.
12. Umida, O., Shakar, N., Alizot, R., Shakhnoza, K., Guloyim, A., Mekhriddin, U., ... & Khurshida, N. (2025). CRISPR-Cas9 gene editing for the long-term control of essential hypertension: preclinical advances and clinical perspectives. Revista Latinoamericana de Hipertensiòn, 20(8).
13. Saparova, S. (2025). Semasiology: A Study of Meaning. Наука и мировоззрение, 1(43), 157-159.
14. Saparova, U. B. (2022). BOSHLANG ‘ICH SINF O ‘QUVCHILARINING IJODIY QOBILIYATINI RIVOJLANTIRISHNING IJTIMOIY PSIXOLOGIK XUSUSIYATLARI. Oriental renaissance: Innovative, educational, natural and social sciences, 2(9), 239-244.
15. Safarova, U. (2019). Structural models of verb contaminated formations. Scientific researches for development future, 65.
16. Saparova, U. B. TARBIYA FANI ASOSIDA BO’LAJAK BOSHLANG ‘ICH SINF O ‘QITUVCHILARIDA IQTISODIY TARBIYA KO ‘NIKMALARINI SHAKLLANTIRISHDA SHARQ MUTAFAKKIRLARI TARIXIY MEROSINING O ‘RNI. МУҒАЛЛИМ ҲӘМ ҮЗЛИКСИЗ БИЛИМЛЕНДИРИЎ, 484.
17. Maftuna, S., & Baxromovna, S. U. (2026). BOSHLANG ‘ICH TAʼLIMDA OTA-ONALAR BILAN HAMKORLIK O ‘RNATISHNING PEDAGOGIK–PSIXOLOGIK OMILLARI. AMERICAN JOURNAL OF EDUCATION AND LEARNING, 4(2), 1-5.
18. Safarova, U. (2025). PROSPECTS AND PROBLEMS OF TOURISM DEVELOPMENT IN UZBEKISTAN IN A DIGITAL AND INNOVATIVE ECONOMY. Eureka Journal of Computing Science & Digital Innovation, 1(2), 6-12.
19. Rustamovna, N. G., & Bakhromovna, S. U. (2025). THE IMPORTANCE OF A DIFFERENTIATED APPROACH IN DEVELOPING MATHEMATICAL THINKING AMONG PRIMARY SCHOOL STUDENTS. AMERICAN JOURNAL OF MULTIDISCIPLINARY BULLETIN, 3(7), 173-177.
20. Mamatova, S., Kurbanov, M., Kodirov, A., Davronova, G., Safarova, M., Bozorova, L., ... & Abdullayev, B. (2025). Obtaining a new type of polymer materials based on recycled polyethylene waste, sulfur, and melamine. Applied Chemical Engineering, 8(4), 1-9.
21. Baxromovna, S. U. (2025). OILADAGI MUHITNING BOLA TA’LIM-TARBIYASIGA TA’SIRI VA YETUK AVLOD OTA-ONALARI QANDAY BO ‘LISHI KERAK. WORLD OF SCIENCE, 8(8), 78-81.
22. Baxromovna, S. U. (2025). BOSHLANG ‘ICH TA’LIMDA BOLALAR PSIXOLOGIYASI. O'ZBEKISTONDA FANLARARO INNOVATSIYALAR VA ILMIY TADQIQOTLAR JURNALI, 4(43), 77-80.
23. Baxromovna, S. U. (2025). TARBIYA FANLARINI AXBOROT-KOMMUNIKATSIYA TEXNOLOGIYALARI (AKT) ORQALI O ‘QITISHNING ZAMONAVIY YONDASHUVLARI. O'ZBEKISTONDA FANLARARO INNOVATSIYALAR VA ILMIY TADQIQOTLAR JURNALI, 4(43), 66-68.
24. Ruxshona, N., Umida, B., & Baxromovna, S. U. (2025). BOSHLANG ‘ICH SINFLARDA MATEMATIKA FANINI O ‘QITISHDA STEAM TEXNOLOGIYALARINING SAMARADORLIGI. O'ZBEKISTONDA FANLARARO INNOVATSIYALAR VA ILMIY TADQIQOTLAR JURNALI, 4(43), 69-72.
25. Baxromovna, S. U. (2025). NUTQ MADANIYATI—SHAXS MADANIYATINING KO ‘ZGUSI. O'ZBEKISTONDA FANLARARO INNOVATSIYALAR VA ILMIY TADQIQOTLAR JURNALI, 4(43), 73-76.
26. Baxromovna, S. U. (2025). BOSHLANG ‘ICH TA’LIM PEDAGOGIKASI FANINING TARIXI VA RIVOJLANISHI. JOURNAL OF INNOVATIONS IN SCIENTIFIC AND EDUCATIONAL RESEARCH, 8(7), 78-80.
27. Baxromovna, S. U. (2025). PEDAGOGIK JARAYONNING ZAMONAVIY TENDENSIYALARI, KAMCHILIK VA YUTUQLARI. SO ‘NGI ILMIY TADQIQOTLAR NAZARIYASI, 8(7), 93-95.
28. Umida, S., & Mehriniso, B. (2025). ZAMONAVIY TAʼLIM TIZIMIDA BOSHLANG ‘ICH SINFLARDA INTEGRATSION DARSLARNING AHAMIYATI. Global Science Review, 1(2), 128-130.
29. Baxromovna, S. U. (2025). BOSHLANG ‘ICH SINFDA TABIIY FANLARNI O ‘QITISHDA AMALIY METODLARNING QO ‘LLANILISHI. AMERICAN JOURNAL OF EDUCATION AND LEARNING, 3(4), 381-390.
30. Nosirova, D. M., & Namozovna, F. U. (2025). SAFAROVA HILOLA OXUNJONOVNA TAQRIZI OSTIDA LAFONTEN MASALLARINING JANRIY BELGILARI. TA’LIM, TARBIYA VA INNOVATSIYALAR JURNALI, 1(2), 185-190.
31. Saparova, M. (2025). “AL-QISTOSU-L-MUSTAQIM FI ILMI-L-ARUD” ASARINING INGLIZ TILIDAGI TARJIMASI XUSUSIDA. In Conferences (Vol. 1, No. 1).
32. Qizi, S. D. M. (2025). TECHNIQUES TO EVALUATE AND COMBINE CULTURAL ERRORS IN UZBEK AND ENGLISH. Alfraganus, (4 (15)), 15-19.
33. Baxromovna, S. U. (2025). BOSHLANG ‘ICH TA’LIMDA INKLYUZIV TA’LIMNI JORIY ETISHNING NAZARIY ASOSLARI, AHAMIYATI VA AMALIY MUAMMOLARI. AMERICAN JOURNAL OF EDUCATION AND LEARNING, 3(11), 762-767.
34. Pardabaevna, G. F., & Umida, X. (2025). ECOLOGICAL AND GEOGRAPHICAL CHARACTERISTICS OF THE GENUS TURANENA. Eurasian Journal of Medical and Natural Sciences, 5(1), 30-34.
35. Baxromovna, S. U. (2024). BOSHLANG'ICH SINF ONA TILI O'QISH DARSLARIDA O'QUVCHILARNI NUTQINI RIVOJLANTIRISH USULLARI. WORLD OF SCIENCE, 7(11), 318-320.
36. Baxromovna, S. U. (2024). ABDURAUF FITRATNING PEDAGOGIK QARASHLARI,“OILA” ASARIDA TA’LIM-TARBIYAGA OID PEDAGOGIK-DIDAKTIK USLUBLARI. O'ZBEKISTONDA FANLARARO INNOVATSIYALAR VA ILMIY TADQIQOTLAR JURNALI, 3(34), 317-322.
37. Sharapova, N. E. (2024). MODERN DIAGNOSTICS OF RESISTANT ARTERIAL HYPERTENSION. EUROPEAN JOURNAL OFMODERNMEDICINEAND PRACTICE, 4(11), 436-442.
38. Saparova, U., & Mavluda, S. (2024). TABIIY FANLARNI OQITISHDA PREDMETLI DARSLARNING AHAMIYATI. SO ‘NGI ILMIY TADQIQOTLAR NAZARIYASI, 7(11), 206-209.
39. Sharapova, N. E. (2024). Acute Bronchitus: Causes, Simptoms, and Triatment with Home Remedies. American Journal of Bioscience and Clinical Integrity, 1(10), 77-84.
40. Aliaskarovna, S. U. (2024). Continuum of Phrases and Phraseological Units in French Language. Central Asian Journal of Literature, Philosophy and Culture, 5(4), 168-171.
